Nexium capsules should be taken at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Your doctor will tell you how long it will take to feel the full benefit of Nexium. Esomeprazole works best if taken on an empty stomach at least one hour before meals and at the same time every day. Your doctor will tell you how long it will take to feel the full benefit of Nexium.
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